Welcome to the web site for the Kallmann Syndrome Organisation.
Kallmann syndrome is a rare hormonal condition that belongs to a group of conditions known as hypogonadotrophic hypogonadism.
Hypogonadotrophic hypogonadism is characterised by a failure to start or to fully complete puberty naturally and can affect both men and women. In most cases, hypogonadotrophic hypogonadism can be successfully treated by means of specialised hormone replacement therapy.
Without treatment people with this condition will very likely be infertile and have an increased risk of developing osteoporosis or 'brittle bones'. With the correct diagnosis and treatment, fertility can be achieved in many cases and the risk of osteoporosis reduced.
One form of hypogonadotrophic hypogonadism is known as Kallmann syndrome which has the additional characteristic of an absent or abnormally low sense of smell. There are a range of conditions that fall under the category of hypogonadotrophic hypogonadism (HH) and it is important to receive specialist medical advice so that the correct diagnosis can be reached and appropriate treatment given.
Kallmann syndrome and other related HH conditions are congenital conditions and as such are present from birth. However the genetic basis of these conditions is not fully understood. Kallmann syndrome and HH can be inherited through the generations but it is sometimes very difficult for doctors to predict if this will occur.
This web site has been set up to provide information for patients with Kallmann syndrome and their family and friends in additional to any health care professionals keen to learn more about this rare condition.