Journal of Clinical Investigation. 10.1172

Digenic mutations account for variable phenotypes in idiopathic hypogonadotrophic hypogonadism.

Research article outlining a new model that suggests that KS and HH can be caused by two separate gene mutations rather than just one.

This study was a joint study between three research groups:

Reproductive Endocrinology Unit, Massachusetts General Hospital, Boston. (Dr Nelly Pitteloud)

Department of Endocrinology, Royal Victoria Hospital, Newcastle, UK.
(Dr Richard Quinton)

Department of Endocrinology, Royal Free Hospital, London, UK.
(Professor Pierre Bouloux)