The main characteristic of hypogonadotrophic hypogonadism is the absence of sexual development.

However on top of this more obvious feature there are other characteristics which while not unique to Kallmann’s syndrome or other forms of HH they can lead a specialist endocrinologist to a correct diagnosis and differentiation from a simple case of delayed puberty.

These characteristics are not seen in all cases of Kallmann syndrome or HH and they all can occur dure to other conditions.

However a combination of delayed puberty with a lack of sense of smell with a history of un-descended testes at birth should alert a doctor to suspect Kallmann syndrome rather than just dismiss it as delayed puberty.

Some of these terms are described in more detail in Q14 of the FAQ’s.

Eunuchoidism – (see Q12 in FAQ)

Cryptorchidism – un-descended testicles at birth

Small genitalia – micro penis, normally classed as an erect length of 1 inch or less

Osteoporosis or brittle bones, especially in older people – (see Q13 in FAQ)

Bimanual synkinesis – mirror movements in the hands

Unilateral renal agenesis – absence of one kidney

Gynaecomastia – enlarged breast tissue in males

Cleft palette, hair lip & other facial deformities

Family history of delayed puberty